CLARITY GENOMICS
HOST-MICROBIOME INTERACTIONS ANALYSIS FOR MICROBIOME-BASED THERAPEUTICS DEVELOPMENT.
What We Do
Longitudinal microbiome-metabolome data analysis and bioinformatics support for microbiome-based therapeutics development.
LONGITUDINAL MICROBIOME AND METABOLOME DATA ANALYSIS AND HOST RESPONSE
MECHANISMS OF HOST-MICROBIOME INTERACTIONS IN DRUG METABOLISM
MICROBIOME AND METABOLOME MACHINE LEARNING ON DISEASE BIOMARKER DISCOVERY COHORTS
How We Do It
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Identification of molecules or species predictive of response
Statistical analysis to identify microbes, metabolites or proteins predictive of metadata responses (such as disease phenotype, sample time collection, protein measurements in blood).
2D/3D molecular and microbial mapping
2D/3D molecular or microbiome cartography to view spatial distribution of molecules or microbes on the sample surface.
Untargeted metabolomics for novel molecule biomarker leads
MS/MS spectra from untargeted liquid or gas chromatography mass spectrometry are explored beyond simple library matching using molecular networking and in silico screening.
Machine learning on control and disease cohorts
Predictive analytics models using machine learning and covariate analysis on public and private cohorts for specific disease types.
Microbiome-metabolome or proteome correlation analysis
Paired samples are analyzed to identify significant correlations between microbes, metabolites or proteins, yielding insight into microbial-derived metabolites and their metabolic pathways.
Small molecule profiling of microbial cultures
Small molecule profiling of microbial cultures via mass spectrometry for metabolite provenance identification in molecular networking.
Who We Are
Bringing together experts in mass spectrometry and DNA sequencing to elucidate how human microbiota communicate with their host and provide valuable insights for clinical research.
Evguenia Kopylova
Managing Director
Creating advanced analytical algorithms to accelerate the development of microbiome-based therapeutics.
Alexey Melnik
Metabolomics Lead
Biomarker discovery within microbial communities using mass spectrometry methods and computational approaches.
Josh Daulton
Marketing & Analytics Lead
Statistical programming to automate marketing processes and optimize performance of sales enablement initiatives.
Rayan Chikhi
Genome Assembly Lead
Developing big data computation algorithms and optimizing tools for analysis of DNA sequencing data.
Zhenjiang Zech Xu
NGS Analysis Adviser
Machine learning development for biomarker identification in metatranscriptome and metagenome sequencing data.
Ajay Kshatriya
Business Adviser
Pioneering genomics in new markets as founder/CEO. Formerly a VC at XSeed Capital and senior manager at Genentech.
Alexander Aksenov
Metabolomics Adviser
Bioanalytical chemistry with a focus on biomarker discovery and chemical aspects of biological processes.
Nicola Segata
NGS Analysis Adviser
Employing experimental meta'omic tools and novel computational approaches to study the diversity of the microbiome.
Clarity Genomics is honored to collaborate with world-leading experts in microbiome analysis:
Caporaso Lab
Northern Arizona University
Our clients include pharmaceutical, consumer products, biotech companies and universities developing microbiome-based therapeutics.