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CLARITY GENOMICS

HOST-MICROBIOME INTERACTIONS ANALYSIS FOR MICROBIOME-BASED THERAPEUTICS DEVELOPMENT.

Services

What We Do

Longitudinal microbiome-metabolome data analysis and bioinformatics support for microbiome-based therapeutics development. 

LONGITUDINAL MICROBIOME AND METABOLOME DATA ANALYSIS AND HOST RESPONSE

MECHANISMS OF HOST-MICROBIOME INTERACTIONS IN DRUG METABOLISM

MICROBIOME AND METABOLOME MACHINE LEARNING ON DISEASE BIOMARKER DISCOVERY COHORTS

How We Do It

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Identification of molecules or species predictive of response

Statistical analysis to identify microbes, metabolites or proteins predictive of metadata responses (such as disease phenotype, sample time collection, protein measurements in blood). 

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2D/3D molecular and microbial mapping

2D/3D molecular or microbiome cartography to view spatial distribution of molecules or microbes on the sample surface.

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Untargeted metabolomics for novel molecule biomarker leads

MS/MS spectra from untargeted liquid or gas chromatography mass spectrometry are explored beyond simple library matching using molecular networking and in silico screening.

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Machine learning on control and disease cohorts

Predictive analytics models using machine learning and covariate analysis on public and private cohorts for specific disease types.

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Microbiome-metabolome or proteome correlation analysis

Paired samples are analyzed to identify significant correlations between microbes, metabolites or proteins, yielding insight into microbial-derived metabolites and their metabolic pathways.

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Small molecule profiling of microbial cultures

Small molecule profiling of microbial cultures via mass spectrometry for metabolite provenance identification in molecular networking.

Team

Who We Are

Bringing together experts in mass spectrometry and DNA sequencing to elucidate how human microbiota communicate with their host and provide valuable insights for clinical research.

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Evguenia Kopylova

Managing Director

Creating advanced analytical algorithms to accelerate the development of microbiome-based therapeutics.

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Alexey Melnik

Metabolomics Lead

Biomarker discovery within microbial communities using mass spectrometry methods and computational approaches.

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Josh Daulton

Marketing & Analytics Lead

Statistical programming to automate marketing processes and optimize performance of sales enablement initiatives.

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Rayan Chikhi

Genome Assembly Lead

Developing big data computation algorithms and optimizing tools for analysis of DNA sequencing data.

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Zhenjiang Zech Xu

NGS Analysis Adviser

Machine learning development for biomarker identification in metatranscriptome and metagenome sequencing data.

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Ajay Kshatriya

Business Adviser

Pioneering genomics in new markets as founder/CEO. Formerly a VC at XSeed Capital and senior manager at Genentech.

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Alexander Aksenov

Metabolomics Adviser

Bioanalytical chemistry with a focus on biomarker discovery and chemical aspects of biological processes.

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Nicola Segata

NGS Analysis Adviser

Employing experimental meta'omic tools and novel computational approaches to study the diversity of the microbiome.

Clarity Genomics is honored to collaborate with world-leading experts in microbiome analysis:

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Caporaso Lab
Northern Arizona University

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Our clients include pharmaceutical, consumer products, biotech companies and universities developing microbiome-based therapeutics.

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